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The Liver
Biology and Pathobiology
FIFTH EDITION
Irwin M. Arias, Harvey J. Alter, James L. Boyer, David E. Cohen, Nelson Fausto, David A. Shafritz, Allen W. Wollkof
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This brand new edition of The Liver: Biology and Pathobiology will once again serve as the premier textbook of basic science hepatology.
By exploring the advances in genetics, immunology, chemistry, virology, biophysics, and structural, molecular and cellular biology, this textbook will help improve understanding of liver function and the nature of liver disease.
With emphasis placed on the impact of genomics, proteomics, combinatorial chemistry, micro-imaging, stem cell biology, and other advances in basic biology on hepatology, the book will be a useful tool for all those interested in the diagnosis, treatment, and prevention of liver disease.
Clearly structured, each chapter is organized around six major headings: Introduction (organizational principles of the liver and embryology), The Cells, Interrelated cell functions, Relation to other organs, Pathobiologic analysis, Horizons.
With an outstanding editorial team who have brought together an internationally recognized collection of contributors, The Liver: Biology and Pathobiology will continue the tradition of previous editions in effectively bridging the many advances in basic science with mechanisms of liver function and disease.
As such, it will be essential reading for basic and clinical scientists, PhD students and fellows, and academic physicians interested in the study of the liver.
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Select a chapter from the list below, to see free sample chapters from the previous editions. (All chapters are in PDF format.)
Apoptosis: Mechanisms and Relevance in Liver Diseases – Fifth Edition Harmeet Malhi, Gregory J. Gores
5. Gene regulation and in vivo function of liver transcription factors – Fourth Edition Robert H. Costa, AI-Xuan Le Holternan, Francisco M. Rausa, Guy R. Adami
16. Energy Metabolism – Third Edition
18. Hypoxic, Ischemic and reperfusion injury to liver – Fourth Edition John J. Lemasters
19. Protective mechanisms against reactive oxygen species – Fourth Edition Masayasu Inoue
20. Disorders of bilirubin metabolism – Fourth Edition Namita Roy Chowdhury, Irwin M. Arias, Allan W. Wolkoff, Jayanta Roy Chowdhury
21. The porphyrias – Fourth Edition Peter N. Meissner, Richard J. Hift, Ralph E. Kirsch
27. Hormonal regulation of bile secretion – Fourth Edition Francis R. Simon
28. Nucleotide transport and regulation of bile formation – Fourth Edition Richard M. Roman and J. Gregory Fitz
30. Endothelial and pit cells – Fourth Edition Filip Braet, Dianzhong Luo, Ilan Spector, David Vermijlen, Eddie Wisse
35 Synthesis of and signalling through D-3 phosphoinositides – Fourth Edition Rial A Christensen, Isabel De Aos Scherpenseel, Lyuba Varticovski
38. Ca2+ signaling in the liver – Fourth Edition Maria De Fatima Leite, Michael H. Nathanson
39. Nitric oxide in the liver – Fourth Edition Mark G. Clemens
40. Interleukin-6 signaling during the acute-phase response of the liver – Fourth Edition Johannes G. Bode, Peter C. Heinrich
41. Innate immune sensing and the toll-like receptors – Fourth Edition Bruce Beutler
42. Liver regeneration – Fourth Edition Nelson Fausto
43. Hepatocyte growth factor: its role in hepatic growth and pathobiology – Fourth Edition Reza Zarnegar, Marie C. Defrances, George K. Michalopoulos
48. Alpha 1-Antitrypsin deficiency – Fourth Edition David H. Perlmutter
63. Novel strategies for manipulating hepatic gene expression in vivo – Fourth Edition Marxa L. Figueiredo, Eric P. Sandgren
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